The body becomes more efficient at metabolizing the alcohol — the process is up to 72% faster in alcoholics — so it takes more booze to achieve the same drunken state. But since alcohol is a diuretic (it stimulates urination), water leaves your body at a higher rate, so your liver must obtain water from other organs, including your brain, which essentially leaves you high and dry. This can change according to how much you had to eat before, your body mass, your gender (men metabolize faster), your age, how hydrated you are, and how efficient your liver is (alcoholics tend to eliminate alcohol faster, though this changes once the liver becomes damaged). Despite a widespread myth that combining antibiotics and alcohol can be dangerous, alcohol can only diminish the efficiency of a few antibiotics, namely metronidazole, cefamandole and oral ketoconazole. read more
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